Interrupting the disease cycle of Psuedogymnoascus destructans (Pd): Leveraging knowledge of disease and treatment dynamics to design integrated disease management strategies.
- PI: Sarah Hooper, Veterinary Pathobiology
- Sponsor: US Forest Service
- Award Amount: $129,878
- To increase bat survival and maintain genetic diversity of remaining populations and to disrupt pathogenic mechanisms and promote development of resistance and/or tolerance within recovering bat populations.
Efficacy of gene therapy drugs in the Pirc rat colorectal cancer model
- PI: James Amos Landgraf, Veterinary Pathobiology
- Sponsor: DNALite Therapeutics, Inc.
- Award Amount: $20,424
- To test the efficacy of gene therapy drugs in an animal model of Familial Adenomatous Polyposis. The animal model will be monitored both longitudinally and post-necropsy for the burden of adenomas.
Evaluation of an implantable vascular occlusion device on distal limb blood flow in a sheep model
- PI: John Middleton, Veterinary Medicine & Surgery
- Sponsor: Dr. Vito Mantese
- Award Amount: $2,840
- To participate in a vascular device implant study with sheep. MU will provide the surgical facilities and supplies and use of an ultrasound machine.
Postdoctoral Training in Comparative Medicine
- PI: Craig Franklin, Veterinary Pathobiology
- Sponsor: NIH
- Award Amount: $215,155
- To provide mentored research experience for trainees in the laboratories of established investigators and a substantive foundation for a competitive research career.
Blood Culture and Blood Microbiome as Minimally Invasive Surrogates for Canine Bacterial Pneumonia
- PI: Carol Reinero, Veterinary Medicine & Surgery
- Sponsor: AKC Canine Health Foundation
- Award Amount: $11,394
- To determine if blood cultures, acting as a surrogate for bronchoalveolar lavage fluid (BALF)analysis, can identify the bacteria causing pneumonia and provide antibiotic susceptibility information and to compare BALF and blood microbiomes.
Shelter Cat Adoption in Families of Children with Autism: Impact on Cat Stress and Children’s Social Skills and Anxiety
- PI: Gretchen Carlisle, Veterinary Medicine & Surgery
- Sponsor: Winn Feline Foundation Inc.
- Award Amount: $24,996
- To study stress of cats living in families of children with Autism Spectrum Disorder (ASD), examine the social skills and anxiety of the children with ASD, and bonding of the parents and children with their cats.
Elemental Enzymes- Brown Collaboration 1
- PI: Charles Brown, Veterinary Pathobiology
- Sponsor: Elemental Enzymes
- Award Amount: $43,522
- To test the immunogenicity of a novel adjuvant system. Creation of an adjuvant that primes the mucosal and systemic immune responses would be advantageous in vaccination.
Targeting the Tick-Pathogen Interface for Tick-Borne Disease Control
- PI: Bill Stich, Veterinary Pathobiology
- Sponsor: NIFA
- Award Amount: $460,000
- To decrease pathogen maintenance and transmission by infected ticks through host immunization with tick salivary gland extract and reduce pathogen acquisition by uninfected ticks through host immunization with tick midgut extract.
A Large Animal model of IGHMBP2: understanding disease development
- PI: Monique Lorson, Veterinary Pathobiology
- Sponsor: KC Area Life Sciences Institute
- Award Amount: $50,001
- To develop an animal model in pigs that will allow researchers to examine disease development and differences between SMA with Respiratory Distress I (SMARD1) and Charcot Marie Tooth Type 2 (CMT2) and provide a tool for the testing of potential therapeutics.